Cell-free mitochondrial DNA may predict the risk of post-operative complications and outcomes in surgical aortic valve replacement patients

Cell-free mitochondrial DNA may predict the risk of post-operative complications and outcomes in surgical aortic valve replacement patients

Abstract Surgical aortic valve replacement (AVR) is the standard of care for severe aortic valve disease; however, post-operative complications continue to pose challenges. Inflammation caused by increased release of cell-free mitochondrial DNA (cf-mtDNA) during surgery may be a contributing factor....

Full description

Saved in:
Bibliographic Details
Main Authors: Kieran Hyslop, Katrina K. Ki, Rishendran Naidoo, Donalee O’Brien, Anil Prabhu, Denzil Gill, Chris Anstey, Ivan L. Rapchuk, Charles I. McDonald, Lachlan Marshall, India Pearse, John F. Fraser, Jacky Y. Suen, Margaret R. Passmore
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Cell-free mitochondrial DNA
Aortic valve replacement
Cardiopulmonary bypass
Inflammation
Severe inflammatory response syndrome
Online Access:https://doi.org/10.1038/s41598-025-00382-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-00382-y

Similar Items