Poor Outcomes in Hepatic Amyloidosis: A Report of 2 Cases
Hepatic amyloidosis is a rare disease entity that results from insoluble amyloid protein deposition in the liver. The disease often presents with vague, nonspecific clinical features. Currently, there is little literature describing treatment outcomes for biopsy-proven hepatic amyloidosis and curren...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/7625940 |
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| _version_ | 1832566931605946368 |
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| author | Brandon Yim Elizabeth Kertowidjojo Yue Zhang Pruthvi Patel |
| author_facet | Brandon Yim Elizabeth Kertowidjojo Yue Zhang Pruthvi Patel |
| author_sort | Brandon Yim |
| collection | DOAJ |
| description | Hepatic amyloidosis is a rare disease entity that results from insoluble amyloid protein deposition in the liver. The disease often presents with vague, nonspecific clinical features. Currently, there is little literature describing treatment outcomes for biopsy-proven hepatic amyloidosis and current treatment guidelines recommend that patients enroll in a clinical trial due to insufficient evidence to suggest an optimal treatment regimen. Here, we present two cases of hepatic amyloidosis at an academic medical center and describe their presentation, treatment, and outcomes. These cases highlight the poor outcomes and difficult management of hepatic amyloidosis. Further understanding and investigation of this rare disease are warranted. |
| format | Article |
| id | doaj-art-f0226c1ce164440d9d6a2c9c3eac9cf0 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-f0226c1ce164440d9d6a2c9c3eac9cf02025-02-03T01:02:48ZengWileyCase Reports in Oncological Medicine2090-67062090-67142016-01-01201610.1155/2016/76259407625940Poor Outcomes in Hepatic Amyloidosis: A Report of 2 CasesBrandon Yim0Elizabeth Kertowidjojo1Yue Zhang2Pruthvi Patel3Department of Medicine, Stony Brook University Hospital, Stony Brook, NY, USADepartment of Pathology, Stony Brook University Hospital, Stony Brook, NY, USADivision of Hematology and Oncology, Department of Medicine, Stony Brook University Hospital, Stony Brook, NY, USADivision of Gastroenterology, Department of Medicine, Stony Brook University Hospital, Stony Brook, NY, USAHepatic amyloidosis is a rare disease entity that results from insoluble amyloid protein deposition in the liver. The disease often presents with vague, nonspecific clinical features. Currently, there is little literature describing treatment outcomes for biopsy-proven hepatic amyloidosis and current treatment guidelines recommend that patients enroll in a clinical trial due to insufficient evidence to suggest an optimal treatment regimen. Here, we present two cases of hepatic amyloidosis at an academic medical center and describe their presentation, treatment, and outcomes. These cases highlight the poor outcomes and difficult management of hepatic amyloidosis. Further understanding and investigation of this rare disease are warranted.http://dx.doi.org/10.1155/2016/7625940 |
| spellingShingle | Brandon Yim Elizabeth Kertowidjojo Yue Zhang Pruthvi Patel Poor Outcomes in Hepatic Amyloidosis: A Report of 2 Cases Case Reports in Oncological Medicine |
| title | Poor Outcomes in Hepatic Amyloidosis: A Report of 2 Cases |
| title_full | Poor Outcomes in Hepatic Amyloidosis: A Report of 2 Cases |
| title_fullStr | Poor Outcomes in Hepatic Amyloidosis: A Report of 2 Cases |
| title_full_unstemmed | Poor Outcomes in Hepatic Amyloidosis: A Report of 2 Cases |
| title_short | Poor Outcomes in Hepatic Amyloidosis: A Report of 2 Cases |
| title_sort | poor outcomes in hepatic amyloidosis a report of 2 cases |
| url | http://dx.doi.org/10.1155/2016/7625940 |
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