Clinical validation of a biopsy‐based six‐gene signature prognostic for aggressive prostate cancer

Clinical validation of a biopsy‐based six‐gene signature prognostic for aggressive prostate cancer

Abstract Objectives This study aimed to clinically validate the six‐gene prognostic molecular clinical risk score (MCRS) for the prediction of aggressive prostate cancer in diagnostic biopsy tissue. Methods MCRS was evaluated in prostate biopsy tissue from a Swedish cohort of men with prostate cance...

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Main Authors: Agnieszka Krzyzanowska, Debra F. Higgins, Stephen Barron, Tony Loughman, Amanda O'Neill, Katherine M. Sheehan, Chan‐Ju Angel Wang, Bozena Fender, Leah McGuire, Joanna Fay, Anthony O'Grady, Des O'Leary, R. William Watson, Anders Bjartell, William M. Gallagher
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:BJUI Compass
Subjects:
gene expression signature
molecular risk score
patient management
prognosis
prostate cancer
risk stratification
Online Access:https://doi.org/10.1002/bco2.474
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https://doi.org/10.1002/bco2.474

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