Understanding Fetal Alcohol Spectrum Disorders (FASDs): Toward Identification of a Behavioral Phenotype

Fetal alcohol spectrum disorders (FASDs) currently represent the leading cause of mental retardation in North America, ahead of Down syndrome and cerebral palsy. The damaging effects of alcohol on the developing brain have a cascading impact on the social and neurocognitive profiles of affected indi...

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Main Authors: Kelly Nash, Erin Sheard, Joanne Rovet, Gideon Koren
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2008.75
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author Kelly Nash
Erin Sheard
Joanne Rovet
Gideon Koren
author_facet Kelly Nash
Erin Sheard
Joanne Rovet
Gideon Koren
author_sort Kelly Nash
collection DOAJ
description Fetal alcohol spectrum disorders (FASDs) currently represent the leading cause of mental retardation in North America, ahead of Down syndrome and cerebral palsy. The damaging effects of alcohol on the developing brain have a cascading impact on the social and neurocognitive profiles of affected individuals. Researchers investigating the profiles of children with FASDs have found impairments in learning and memory, executive functioning, and language, as well as hyperactivity, impulsivity, poor communication skills, difficulties with social and moral reasoning, and psychopathology. The primary goal of this review paper is to examine current issues pertaining to the identification of a behavioral phenotype in FASDs, as well as to address related screening and diagnostic concerns. We conclude that future research initiatives comparing children with FASDs to nonalcohol-exposed children with similar cognitive and socioemotional profiles should aid in uncovering the unique behavioral phenotype for FASDs.
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spelling doaj-art-eff8d4dd2a31473ea45811a032bb48302025-02-03T01:30:40ZengWileyThe Scientific World Journal1537-744X2008-01-01887388210.1100/tsw.2008.75Understanding Fetal Alcohol Spectrum Disorders (FASDs): Toward Identification of a Behavioral PhenotypeKelly Nash0Erin Sheard1Joanne Rovet2Gideon Koren3The Hospital for Sick Children, Toronto and the Ontario Institute for Studies in Education, University of Toronto, Toronto, CanadaThe Hospital for Sick Children, Toronto and the Ontario Institute for Studies in Education, University of Toronto, Toronto, CanadaThe Hospital for Sick Children, Toronto and the Ontario Institute for Studies in Education, University of Toronto, Toronto, CanadaThe Hospital for Sick Children, Toronto and the Ontario Institute for Studies in Education, University of Toronto, Toronto, CanadaFetal alcohol spectrum disorders (FASDs) currently represent the leading cause of mental retardation in North America, ahead of Down syndrome and cerebral palsy. The damaging effects of alcohol on the developing brain have a cascading impact on the social and neurocognitive profiles of affected individuals. Researchers investigating the profiles of children with FASDs have found impairments in learning and memory, executive functioning, and language, as well as hyperactivity, impulsivity, poor communication skills, difficulties with social and moral reasoning, and psychopathology. The primary goal of this review paper is to examine current issues pertaining to the identification of a behavioral phenotype in FASDs, as well as to address related screening and diagnostic concerns. We conclude that future research initiatives comparing children with FASDs to nonalcohol-exposed children with similar cognitive and socioemotional profiles should aid in uncovering the unique behavioral phenotype for FASDs.http://dx.doi.org/10.1100/tsw.2008.75
spellingShingle Kelly Nash
Erin Sheard
Joanne Rovet
Gideon Koren
Understanding Fetal Alcohol Spectrum Disorders (FASDs): Toward Identification of a Behavioral Phenotype
The Scientific World Journal
title Understanding Fetal Alcohol Spectrum Disorders (FASDs): Toward Identification of a Behavioral Phenotype
title_full Understanding Fetal Alcohol Spectrum Disorders (FASDs): Toward Identification of a Behavioral Phenotype
title_fullStr Understanding Fetal Alcohol Spectrum Disorders (FASDs): Toward Identification of a Behavioral Phenotype
title_full_unstemmed Understanding Fetal Alcohol Spectrum Disorders (FASDs): Toward Identification of a Behavioral Phenotype
title_short Understanding Fetal Alcohol Spectrum Disorders (FASDs): Toward Identification of a Behavioral Phenotype
title_sort understanding fetal alcohol spectrum disorders fasds toward identification of a behavioral phenotype
url http://dx.doi.org/10.1100/tsw.2008.75
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