Determination of Five Coumarins in Angelicae Pubescentis Radix from Different Origins by HPTLC-Scanning
The HPTLC method is widely used in the field of quality evaluation and component analysis of traditional Chinese medicine (TCM). This work developed an HPTLC method to determine the five effective components of osthole, columbianadin, isoimperatorin, oxypeucedanin, and imperatorin in Angelicae Pubes...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Analytical Methods in Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2022/3415938 |
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| author | Dangtong Ji Qian Li Hanting Yang Yue Fan Ting Wang Yuying Chen |
| author_facet | Dangtong Ji Qian Li Hanting Yang Yue Fan Ting Wang Yuying Chen |
| author_sort | Dangtong Ji |
| collection | DOAJ |
| description | The HPTLC method is widely used in the field of quality evaluation and component analysis of traditional Chinese medicine (TCM). This work developed an HPTLC method to determine the five effective components of osthole, columbianadin, isoimperatorin, oxypeucedanin, and imperatorin in Angelicae Pubescentis Radix (APR) from twelve different origins, and the quality difference was analyzed by comprehensive factor analysis and cluster analysis. The results showed that the calibration curves of five components exhibited good linearity within the linear ranges (0.8–4.0 μg). The RSD of precision was 1.06%–1.21%, and the repeatability and stability tests were good. The results of cluster analysis showed that the APR from 12 different areas was divided into two categories, and at the same time, it was found that the quality of Dazhou in Sichuan and Huating in Gansu was better than in other areas. In this study, a simple, rapid, and efficient method for quality evaluation of TCM was established by the HPTLC method. |
| format | Article |
| id | doaj-art-eff1ba8ce75747b0b62d846626d04fd5 |
| institution | Kabale University |
| issn | 2090-8873 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Analytical Methods in Chemistry |
| spelling | doaj-art-eff1ba8ce75747b0b62d846626d04fd52025-02-03T05:50:39ZengWileyJournal of Analytical Methods in Chemistry2090-88732022-01-01202210.1155/2022/3415938Determination of Five Coumarins in Angelicae Pubescentis Radix from Different Origins by HPTLC-ScanningDangtong Ji0Qian Li1Hanting Yang2Yue Fan3Ting Wang4Yuying Chen5State Key Laboratory of Aridland Crop ScienceState Key Laboratory of Aridland Crop ScienceState Key Laboratory of Aridland Crop ScienceState Key Laboratory of Aridland Crop ScienceState Key Laboratory of Aridland Crop ScienceState Key Laboratory of Aridland Crop ScienceThe HPTLC method is widely used in the field of quality evaluation and component analysis of traditional Chinese medicine (TCM). This work developed an HPTLC method to determine the five effective components of osthole, columbianadin, isoimperatorin, oxypeucedanin, and imperatorin in Angelicae Pubescentis Radix (APR) from twelve different origins, and the quality difference was analyzed by comprehensive factor analysis and cluster analysis. The results showed that the calibration curves of five components exhibited good linearity within the linear ranges (0.8–4.0 μg). The RSD of precision was 1.06%–1.21%, and the repeatability and stability tests were good. The results of cluster analysis showed that the APR from 12 different areas was divided into two categories, and at the same time, it was found that the quality of Dazhou in Sichuan and Huating in Gansu was better than in other areas. In this study, a simple, rapid, and efficient method for quality evaluation of TCM was established by the HPTLC method.http://dx.doi.org/10.1155/2022/3415938 |
| spellingShingle | Dangtong Ji Qian Li Hanting Yang Yue Fan Ting Wang Yuying Chen Determination of Five Coumarins in Angelicae Pubescentis Radix from Different Origins by HPTLC-Scanning Journal of Analytical Methods in Chemistry |
| title | Determination of Five Coumarins in Angelicae Pubescentis Radix from Different Origins by HPTLC-Scanning |
| title_full | Determination of Five Coumarins in Angelicae Pubescentis Radix from Different Origins by HPTLC-Scanning |
| title_fullStr | Determination of Five Coumarins in Angelicae Pubescentis Radix from Different Origins by HPTLC-Scanning |
| title_full_unstemmed | Determination of Five Coumarins in Angelicae Pubescentis Radix from Different Origins by HPTLC-Scanning |
| title_short | Determination of Five Coumarins in Angelicae Pubescentis Radix from Different Origins by HPTLC-Scanning |
| title_sort | determination of five coumarins in angelicae pubescentis radix from different origins by hptlc scanning |
| url | http://dx.doi.org/10.1155/2022/3415938 |
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