Adsorption of Atenolol on Talc: An Indication of Drug Interference with an Excipient

Talc is commonly used as an excipient for drug formulations. The general expectation is that the excipient should have only minimal interactions with the carrying drug. In this study, the adsorption of atenolol (AT), a β-blocker, on talc, a clay mineral of pH-dependent surface charge, was evaluated...

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Bibliographic Details
Main Authors: Zhaohui Li, Nicole M. Fitzgerald, Guocheng Lv, Wei-Teh Jiang, Limei Wu
Format: Article
Language:English
Published: SAGE Publishing 2015-04-01
Series:Adsorption Science & Technology
Online Access:https://doi.org/10.1260/0263-6174.33.4.379
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