Treatment of osteoarthritic knee with high tibial osteotomy and allogeneic human umbilical cord blood–derived mesenchymal stem cells combined with hyaluronate hydrogel composite

Treatment of osteoarthritic knee with high tibial osteotomy and allogeneic human umbilical cord blood–derived mesenchymal stem cells combined with hyaluronate hydrogel composite

Abstract Background Delaying total knee arthroplasty is crucial for middle-aged patients with severe osteoarthritis. The long-term outcomes of high tibial osteotomy (HTO) remain uncertain. Recently, mesenchymal stem cells (MSCs) have shown promising potential in enhancing cartilage regeneration. The...

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Bibliographic Details
Main Authors: Bo Seung Bae, Jae Woong Jung, Gyeong Ok Jo, Seon Ae Kim, Eun Jeong Go, Mi-La Cho, Asode Ananthram Shetty, Seok Jung Kim
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Stem Cell Research & Therapy
Subjects:
Cartilage regeneration
High tibial osteotomy
Mesenchymal stem cell
Osteoarthritis
Online Access:https://doi.org/10.1186/s13287-025-04356-9
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https://doi.org/10.1186/s13287-025-04356-9

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