Protective effects of Bifidobacterium breve on imiquimod-induced psoriasis in mice through secondary bile acid production and FXR-TLR4/NF-κB pathway

Protective effects of Bifidobacterium breve on imiquimod-induced psoriasis in mice through secondary bile acid production and FXR-TLR4/NF-κB pathway

This study aimed to evaluate the effects of Bifidobacterium breve CCFM683 on psoriasis and to investigate the underlying mechanisms. B. breve CCFM683 significantly ameliorated psoriasis in mice as well as elevated the deoxycholic acid (DCA) and lithocholic acid (LCA) in the colon compared with those...

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Bibliographic Details
Main Authors: Xinqi Chen, Yang Chen, Catherine Stanton, R.Paul Ross, Jianxin Zhao, Bo Yang, Wei Chen
Format: Article
Language:English
Published: Tsinghua University Press 2024-11-01
Series:Food Science and Human Wellness
Subjects:
psoriasis
bifidobacterium breve
gut microbiota
secondary bile acids
fxr-tlr4/nf-κb pathway
Online Access:https://www.sciopen.com/article/10.26599/FSHW.2023.9250029
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https://www.sciopen.com/article/10.26599/FSHW.2023.9250029

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