The role of KNDy neurons in human reproductive health

In the early 2000s, metastin, an endogenous ligand for G protein-coupled receptor 54 (GPR54), was discovered in human placental extracts. In 2003, GPR54 receptor mutations were found in a family with congenital hypogonadotropic hypogonadism. Metastin was subsequently renamed kisspeptin after its cod...

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Bibliographic Details
Main Authors: Aki Oride, Haruhiko Kanasaki
Format: Article
Language:English
Published: The Japan Endocrine Society 2024-08-01
Series:Endocrine Journal
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Online Access:https://www.jstage.jst.go.jp/article/endocrj/71/8/71_EJ24-0006/_html/-char/en
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