GABAergic regulation of striatal spiny projection neurons depends upon their activity state.

Synaptic transmission mediated by GABAA receptors (GABAARs) in adult, principal striatal spiny projection neurons (SPNs) can suppress ongoing spiking, but its effect on synaptic integration at subthreshold membrane potentials is less well characterized, particularly those near the resting down-state...

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Bibliographic Details
Main Authors: Michelle Day, Marziyeh Belal, William C Surmeier, Alexandria Melendez, David Wokosin, Tatiana Tkatch, Vernon R J Clarke, D James Surmeier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002483&type=printable
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