CRISPR/Cas9 Reduces Viral Load in a BALB/c Mouse Model of Ocular Herpes Infection

CRISPR/Cas9 Reduces Viral Load in a BALB/c Mouse Model of Ocular Herpes Infection

<b>Background/Objectives</b>: <i>Simplexvirus humanalpha1</i> (HSV-1) can cause herpetic keratitis, which is the most common cause of infectious blindness in developed countries. Some patients can develop toxicity or resistance to available treatments and may require keratopl...

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Bibliographic Details
Main Authors: Luiza Silveira Garcia, Rafaela Moraes Pereira de Sousa, Viviane Souza Campos, Erik Machado Ferreira, Cynthia Machado Cascabulho, Elen Mello de Souza, Vanessa Salete de Paula
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomedicines
Subjects:
herpetic keratitis
CRISPR/Cas9
in vivo model
HSV-1
Online Access:https://www.mdpi.com/2227-9059/13/7/1738
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https://www.mdpi.com/2227-9059/13/7/1738

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