Herb-partitioned moxibustion alleviates colonic inflammation in Crohn's disease rats by inhibiting hyperactivation of the NLRP3 inflammasome via regulation of the P2X7R-Pannexin-1 signaling pathway.

Herb-partitioned moxibustion alleviates colonic inflammation in Crohn's disease rats by inhibiting hyperactivation of the NLRP3 inflammasome via regulation of the P2X7R-Pannexin-1 signaling pathway.

Crohn's disease is a chronic inflammatory bowel disease and the NLRP3 inflammasome plays an important role in Crohn's disease. Previous studies have shown that Herb-partitioned moxibustion treating (at Qihai (CV 6) and Tianshu (ST 25)) prevented the excessive activation of the NLRP3 inflam...

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Main Authors: Ji Zhang, Xue-Jun Wang, Li-Jie Wu, Ling Yang, Yan-Ting Yang, Dan Zhang, Jue Hong, Xi-Ying Li, Xiao-Qing Dong, Xiao-Cong Guo, Rong Han, Xiaopeng Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0252334&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0252334&type=printable

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