Development of a Novel mRNA Vaccine Against Pathotypes Causing Widespread Shigellosis Endemic: An In-Silico Immunoinformatic Approach

Development of a Novel mRNA Vaccine Against Pathotypes Causing Widespread Shigellosis Endemic: An In-Silico Immunoinformatic Approach

Shigellosis remains a major global health concern, particularly in regions with poor sanitation and limited access to clean water. This study used immunoinformatics and reverse vaccinology to design a potential mRNA vaccine targeting Shigella pathotypes out of 4071 proteins from Shigella sonnei str....

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Main Authors: Abdur Razzak, Otun Saha, Khandokar Fahmida Sultana, Mohammad Ruhul Amin, Abdullah bin Zahid, Afroza Sultana, Uditi Paul Bristi, Sultana Rajia, Nikkon Sarker, Md Mizanur Rahaman, Newaz Mohammed Bahadur, Foysal Hossen
Format: Article
Language:English
Published: SAGE Publishing 2025-03-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.1177/11779322251328302
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https://doi.org/10.1177/11779322251328302

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