Preventive treatment with guarana powder (Paullinia cupana) mitigates acute paracetamol-induced hepatotoxicity by modulating oxidative stress

Preventive treatment with guarana powder (Paullinia cupana) mitigates acute paracetamol-induced hepatotoxicity by modulating oxidative stress

Liver damage caused by high doses of paracetamol is a global public health concern. Consequently, therapeutic strategies are being explored to prevent this damage. The bioactive compounds present in fruits have shown promise in protecting against disorders associated with paracetamol-induced liver d...

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Main Authors: Clécia Dias Teixeira, Priscila Oliveira Barbosa, Wanderson Geraldo Lima, Gustavo Silveira Breguez, Miliane Martins de Andrade Fagundes, Daniela Caldeira Costa, Cintia Lopes de Brito Magalhães, Joana Ferreira Amaral, Melina Oliveira de Souza
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Toxicology Reports
Subjects:
Guarana
Hepatotoxicity
Liver injury
Oxidative stress
Paullinia cupana
Paracetamol
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750025000642
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