16S Ribosomal RNA Gene PCR and Sequencing for Pediatric Infection Diagnosis, United States, 2020–2023

16S Ribosomal RNA Gene PCR and Sequencing for Pediatric Infection Diagnosis, United States, 2020–2023

Gene PCR and sequencing using 16S ribosomal RNA (rRNA) can help diagnose challenging bacterial infections. Data on the optimal clinical settings for this type of testing are limited. We performed a retrospective study at Mayo Clinic, Rochester, Minnesota, USA, with typically sterile specimens from...

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Bibliographic Details
Main Authors: Guyu Li, Christopher A. Reis, Rebecca M. Kruc, Ziyuan Zhang, Nicholas T. Streck, Elizabeth H. Ristagno, Jay Mandrekar, Matthew J. Wolf, James T. Gaensbauer, Robin Patel
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2025-05-01
Series:Emerging Infectious Diseases
Subjects:
16S ribosomal RNA
PCR
sequencing
bacteria
bacterial infections
pediatrics
Online Access:https://wwwnc.cdc.gov/eid/article/31/13/24-1101_article
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