Overexpression of Parkin promotes the protective effect of mitochondrial autophagy on the lung of rats with exertional heatstroke

Background: The roles of the Pink1/Parkin pathway and mitophagy in lung injury during heat stroke remain unclear. In this study, we investigated the role of Pink1/Parkin-mediated mitophagy in acute lung injury (ALI) in rats with exertional heat stroke (EHS). Methods: Sixty Sprague Dawley rats were r...

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Bibliographic Details
Main Authors: Ran Meng, Zhengzhong Sun, Ruxue Chi, Yan Gu, Yuxiang Zhang, Jiaxing Wang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Intensive Medicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667100X2400094X
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