Single-cell RNA sequencing identifies CXADR as a fate determinant of the placental exchange surface

Abstract The placenta is the critical interface between mother and fetus, and consequently, placental dysfunction underlies many pregnancy complications. Placental formation requires an adequate expansion of trophoblast stem and progenitor cells followed by finely tuned lineage specification events....

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Main Authors: Dafina M. Angelova, Aleksandra Tsolova, Malwina Prater, Noura Ballasy, Wendi Bacon, Russell S. Hamilton, Danielle Blackwell, Ziyi Yu, Xin Li, Xin Liu, Myriam Hemberger, D. Stephen Charnock-Jones
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55597-w
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