Comparative study of the inhibitory effects of different antibiotic administration routes on bone healing in a rat tibial infection model

Comparative study of the inhibitory effects of different antibiotic administration routes on bone healing in a rat tibial infection model

ObjectiveThis study aimed to evaluate the effectiveness of intravenous versus oral antibiotic treatments in managing bone infections, particularly osteomyelitis, using a rat tibial infection model.MethodsA tibial bone infection model was established in twelve-week-old Wistar rats via injection of St...

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Bibliographic Details
Main Authors: Xiaoyu Han, Wei Wang, Zengli Shen, Lisong Lv, Bingyuan Lin, Haiyong Ren, Yiyang Liu, Qiaofeng Guo, Huang Kai, Xiang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
bone infection
antibiotic treatment
rat model
osteomyelitis
bone healing
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1529692/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1529692/full

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