TRPM2 channels mediate ROS-induced actin remodeling and cell migration of prostate cancer cells

TRPM2 channels mediate ROS-induced actin remodeling and cell migration of prostate cancer cells

Abstract Background Actin remodeling plays important roles in pathophysiological processes such as cancer metastasis and angiogenesis. Reactive oxygen species (ROS) are signaling molecules thought to regulate cell migration by remodeling actin cytoskeleton. Earlier, we demonstrated that Transient re...

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Bibliographic Details
Main Authors: Pengwei Qi, Jingting Zhao, Hongtian Zhang, Xingyu Liu, Qing You, Jianguo Niu, Xiangming Ye, Fangfang Li
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
ROS
TRPM2 channel
Ca2+
Zn2+
Actin remodeling
Cell migration
Online Access:https://doi.org/10.1186/s12885-025-14333-3
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https://doi.org/10.1186/s12885-025-14333-3

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