Modelling adrenal steroid profiles to inform monitoring guidance in congenital adrenal hyperplasiaResearch in context

Modelling adrenal steroid profiles to inform monitoring guidance in congenital adrenal hyperplasiaResearch in context

Summary: Background: There is no consensus on how to monitor adrenal androgens in Congenital Adrenal Hyperplasia (CAH). Methods: Modelling of serum and salivary steroid profiles in healthy participants and patients with CAH randomised to either standard treatment or modified-release hydrocortisone...

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Main Authors: Neil R. Lawrence, Jeremy Dawson, Zi-Qiang Lang, Alessandro Prete, Elizabeth S. Baranowski, Lina Schiffer, Angela E. Taylor, Aude Brac de la Perrière, Angelica Lindén Hirschberg, Anders Juul, Deborah P. Merke, John Newell-Price, D. Aled Rees, Nicole Reisch, Nike Stikkelbroeck, Philippe A. Touraine, Nils Krone, Brian Keevil, Gary S. Collins, Wiebke Arlt, Richard J.M. Ross
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:EBioMedicine
Subjects:
Congenital adrenal hyperplasia
21-Hydroxylase deficiency
Adrenal insufficiency
Hydrocortisone
Glucocorticoid
Modified release hydrocortisone
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425001938
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