VSL#3 Probiotic Upregulates Intestinal Mucosal Alkaline Sphingomyelinase and Reduces Inflammation

VSL#3 Probiotic Upregulates Intestinal Mucosal Alkaline Sphingomyelinase and Reduces Inflammation

BACKGROUND: Alkaline sphingomyelinase, an enzyme found exclusively in bile and the intestinal brush border, hydrolyzes sphingomyelin into ceramide, sphingosine and sphingosine-1-phosphate, thereby inducing epithelial apoptosis. Reduced levels of alkaline sphingomyelinase have been found in premalign...

Full description

Saved in:
Bibliographic Details
Main Authors: Isaac Soo, Karen L Madsen, Qassim Tejpar, Beate C Sydora, Richard Sherbaniuk, Benedetta Cinque, Luisa Di Marzio, Maria Grazia Cifone, Claudio Desimone, Richard N Fedorak
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2008/520383
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items