Transformation of Chronic Myeloid Leukemia to Acute Undifferentiated Leukemia: Case Report and Literature Review

Transformation of Chronic Myeloid Leukemia to Acute Undifferentiated Leukemia: Case Report and Literature Review

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm driven by the BCR::ABL1 fusion gene and typically progresses through chronic, accelerated, and blast crisis phases. While blast crises often present with myeloid or lymphoid phenotypes, transformation to acute undifferentiated leukemia...

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Bibliographic Details
Main Authors: Oussama Grari, Assya Khermach, Nouhaila Chahid, Nisma Douzi, Amina Himri, Abdelilah Berhili, Mounia Slaoui, Nabiha Trougouty, Mohammed Bensalah, Rachid Seddik
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Journal of Applied Hematology
Subjects:
acute undifferentiated leukemia
blast crisis
chronic myeloid leukemia
tyrosine kinase inhibitors
Online Access:https://journals.lww.com/10.4103/joah.joah_53_25
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