The inhibitory effect of anti-allergic agent suplatast tosilate (IPD–1151T) on methacholine- and allergen-induced bronchoconstriction in sensitized mice

The influence of an anti-allergic agent, suplatast tosilate (IPD-1151T; (±)-[2-[4-(3-ethoxy–2-hydroxypropoxy)phenyl-carbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate) on allergic bronchoconstriction induced by allergen and methacholine (MCh) were examined in mice. BALB/c mice were sensitized by...

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Bibliographic Details
Main Authors: Kazuhito Asano, Tetsuya Mizutani, Toshikazu Shimane, Masataka Hisano, Tadashi Hisamitsu, Harumi Suzaki
Format: Article
Language:English
Published: Wiley 2000-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/096293500411532
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