Intranasal recombinant protein subunit vaccine targeting TLR3 induces respiratory tract IgA and CD8 T cell responses and protects against respiratory virus infectionResearch in context

Summary: Background: Intranasal vaccines against respiratory viruses are desired due to ease of administration and potential to protect against virus infection of the upper respiratory tract. Methods: We tested a cationic liposomal adjuvant delivering the TLR3 agonist Poly (I:C) (CAF®09b) for intra...

Full description

Saved in:

Bibliographic Details
Main Authors:	Katharina Wørzner, Signe Tandrup Schmidt, Julie Zimmermann, Ahmad Tami, Charlotta Polacek, Carlota Fernandez-Antunez, Katrine Top Hartmann, Rune Fledelius Jensen, Julia Sid Hansen, Kristin Illigen, Louise Krag Isling, Gitte Erbs, Gregers Jungersen, Ida Rosenkrands, Anna Offersgaard, Judith Gottwein, Kenn Holmbeck, Henrik Elvang Jensen, Santseharay Ramirez, Frank Follmann, Jens Bukh, Gabriel Kristian Pedersen
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Series:	EBioMedicine
Subjects:	SARS-CoV-2 CAF®09b CD8 T cells Intranasal vaccine
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396425000593
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!

Intranasal recombinant protein subunit vaccine targeting TLR3 induces respiratory tract IgA and CD8 T cell responses and protects against respiratory virus infectionResearch in context

Similar Items