Unveiling the molecular profile of a prostate carcinoma: implications for personalized medicine

Unveiling the molecular profile of a prostate carcinoma: implications for personalized medicine

Abstract Background Prostate cancer is the most common diagnosed tumor and the fifth cancer related death among men in Europe. Although several genetic alterations such as ERG-TMPRSS2 fusion, MYC amplification, PTEN deletion and mutations in p53 and BRCA2 genes play a key role in the pathogenesis of...

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Main Authors: Massimiliano Agostini, Erica Giacobbi, Francesca Servadei, Julia Bishof, Likas Funke, Giuseppe Sica, Valentina Rovella, Marco Carilli, Valerio Iacovelli, Yufang Shi, Jianquan Hou, Eleonora Candi, Gerry Melino, Giulio Cervelli, Manuel Scimeca, Alessandro Mauriello, Pierluigi Bove
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Biology Direct
Subjects:
Prostate cancer
KDM6A
Hypoxia
ROS
Immune response
Personalized medicine
Online Access:https://doi.org/10.1186/s13062-024-00492-z
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https://doi.org/10.1186/s13062-024-00492-z

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