Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A randomized, crossover trial
Almonds are a plant-based source of lipids, proteins, fibers, micronutrients, and phytochemicals associated with cardiometabolic health benefits. We examined blood glucose homeostasis, lipid profile, anthropometrics, blood pressure, food cravings, and mood both pre- and post-feeding, using a randomi...
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Elsevier
2025-03-01
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| Series: | Human Nutrition & Metabolism |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666149724000537 |
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| author | Vernon Uganiza Rayo Lauren Okamoto Maricarmen Cervantes Mee Young Hong Nathaniel Jason Mark Kern Changqi Liu Elise North Svitlana Storm Oliver C. Witard Shirin Hooshmand |
| author_facet | Vernon Uganiza Rayo Lauren Okamoto Maricarmen Cervantes Mee Young Hong Nathaniel Jason Mark Kern Changqi Liu Elise North Svitlana Storm Oliver C. Witard Shirin Hooshmand |
| author_sort | Vernon Uganiza Rayo |
| collection | DOAJ |
| description | Almonds are a plant-based source of lipids, proteins, fibers, micronutrients, and phytochemicals associated with cardiometabolic health benefits. We examined blood glucose homeostasis, lipid profile, anthropometrics, blood pressure, food cravings, and mood both pre- and post-feeding, using a randomized, crossover design with 26 healthy adults (37±6 y) consuming either ALMOND (57 g/d) or an isocaloric amount of pretzels (CONTROL) for 8 weeks. Almond supplementation was expected to improve all primary outcomes when compared to CONTROL. ALMOND improved diet quality through increased intakes of monounsaturated fat (Δ+58 %), polyunsaturated fat (Δ+24 %), α-tocopherol (Δ+133 %), β-tocopherol (Δ+33 %), and magnesium (Δ+30 %) relative to CONTROL (Interaction: all p < 0.05). Copper intake increased (Δ+27 %) and sodium decreased (Δ-20 %) during ALMOND (Time: all p < 0.05). A reduction in waist circumference (Δ-1.1 cm) and decrease in carbohydrate intake (Δ-20 %) was observed during ALMOND vs. CONTROL (Trial: all p < 0.05). Insulin sensitivity decreased during CONTROL (Time: p < 0.05) but remained constant during ALMOND. Frequency of food cravings over the last 7 days of experimentation increased during ALMOND vs. CONTROL (Interaction: all p < 0.05). No differences in blood lipid profile, physical activity, and assessments of mood were observed between trials (all p > 0.05). This study demonstrates that a 57 g/d serving of almonds modestly improves diet quality and waist circumference. However, almond supplementation elicited no clinically significant benefits on lipid profile, blood pressure, physical activity, and assessments of cravings and mood. Future mechanistic studies are warranted to understand the effect of almond supplementation on cardiometabolic health in various populations. ClinicalTrials.gov Identifier: NCT04787718. |
| format | Article |
| id | doaj-art-ed4f4b42a2ac4133ae0bbc235f182b64 |
| institution | Kabale University |
| issn | 2666-1497 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Human Nutrition & Metabolism |
| spelling | doaj-art-ed4f4b42a2ac4133ae0bbc235f182b642025-02-06T05:12:47ZengElsevierHuman Nutrition & Metabolism2666-14972025-03-0139200291Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A randomized, crossover trialVernon Uganiza Rayo0Lauren Okamoto1Maricarmen Cervantes2Mee Young Hong3Nathaniel Jason4Mark Kern5Changqi Liu6Elise North7Svitlana Storm8Oliver C. Witard9Shirin Hooshmand10School of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, United States; Corresponding author. School of Exercise and Nutritional Sciences, San Diego State University, United Kingdom.School of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, United StatesSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, United StatesSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, United StatesSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, United StatesSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, United StatesSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, United StatesSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, United StatesSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, United StatesCentre for Human and Applied Physiological Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United KingdomSchool of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, United StatesAlmonds are a plant-based source of lipids, proteins, fibers, micronutrients, and phytochemicals associated with cardiometabolic health benefits. We examined blood glucose homeostasis, lipid profile, anthropometrics, blood pressure, food cravings, and mood both pre- and post-feeding, using a randomized, crossover design with 26 healthy adults (37±6 y) consuming either ALMOND (57 g/d) or an isocaloric amount of pretzels (CONTROL) for 8 weeks. Almond supplementation was expected to improve all primary outcomes when compared to CONTROL. ALMOND improved diet quality through increased intakes of monounsaturated fat (Δ+58 %), polyunsaturated fat (Δ+24 %), α-tocopherol (Δ+133 %), β-tocopherol (Δ+33 %), and magnesium (Δ+30 %) relative to CONTROL (Interaction: all p < 0.05). Copper intake increased (Δ+27 %) and sodium decreased (Δ-20 %) during ALMOND (Time: all p < 0.05). A reduction in waist circumference (Δ-1.1 cm) and decrease in carbohydrate intake (Δ-20 %) was observed during ALMOND vs. CONTROL (Trial: all p < 0.05). Insulin sensitivity decreased during CONTROL (Time: p < 0.05) but remained constant during ALMOND. Frequency of food cravings over the last 7 days of experimentation increased during ALMOND vs. CONTROL (Interaction: all p < 0.05). No differences in blood lipid profile, physical activity, and assessments of mood were observed between trials (all p > 0.05). This study demonstrates that a 57 g/d serving of almonds modestly improves diet quality and waist circumference. However, almond supplementation elicited no clinically significant benefits on lipid profile, blood pressure, physical activity, and assessments of cravings and mood. Future mechanistic studies are warranted to understand the effect of almond supplementation on cardiometabolic health in various populations. ClinicalTrials.gov Identifier: NCT04787718.http://www.sciencedirect.com/science/article/pii/S2666149724000537NutLipid profileAppetiteWell-beingPhysical activityFood craving |
| spellingShingle | Vernon Uganiza Rayo Lauren Okamoto Maricarmen Cervantes Mee Young Hong Nathaniel Jason Mark Kern Changqi Liu Elise North Svitlana Storm Oliver C. Witard Shirin Hooshmand Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A randomized, crossover trial Human Nutrition & Metabolism Nut Lipid profile Appetite Well-being Physical activity Food craving |
| title | Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A randomized, crossover trial |
| title_full | Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A randomized, crossover trial |
| title_fullStr | Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A randomized, crossover trial |
| title_full_unstemmed | Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A randomized, crossover trial |
| title_short | Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A randomized, crossover trial |
| title_sort | almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight middle aged adults a randomized crossover trial |
| topic | Nut Lipid profile Appetite Well-being Physical activity Food craving |
| url | http://www.sciencedirect.com/science/article/pii/S2666149724000537 |
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