Deciphering the causality of gut microbiota, circulating metabolites and heart failure: a mediation mendelian

BackgroundGrowing evidence suggesting a connection between the gut microbiome, plasma metabolites, and the development of heart failure (HF). However, the causality of this relationship remains to be fully elucidated.MethodsUtilizing summary statistics from extensive genome-wide association studies...

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Bibliographic Details
Main Authors: Xueqing Guan, Chaonan Sun, Jianyao Su, Zhijun Sun, Cheng Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1531384/full
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