A chalcone/quinolone hybrid drug (COQM) triggers oxidative stress, DNA damage, and apoptosis to induce selective antiproliferative effects in breast cancer cells

COQM is a newly developed hybrid compound of chalcone and quinolone, both of which are known to have anticancer and anti-inflammatory abilities. However, the anticancer effect of COQM on breast cancer cells is not yet well understood, and its safety has not been fully investigated. In this study, we...

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Bibliographic Details
Main Authors: Jun-Ping Shiau, Wangta Liu, Chih-Hua Tseng, Min-Yu Lee, Cheng-Yao Yang, Yu-Ning Wang, Hsueh-Wei Chang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Results in Chemistry
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625002516
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