The Importance of Magnesium in Clinical Healthcare

The scientific literature provides extensive evidence of widespread magnesium deficiency and the potential need for magnesium repletion in diverse medical conditions. Magnesium is an essential element required as a cofactor for over 300 enzymatic reactions and is thus necessary for the biochemical f...

Full description

Saved in:
Bibliographic Details
Main Authors: Gerry K. Schwalfenberg, Stephen J. Genuis
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2017/4179326
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832555502600454144
author Gerry K. Schwalfenberg
Stephen J. Genuis
author_facet Gerry K. Schwalfenberg
Stephen J. Genuis
author_sort Gerry K. Schwalfenberg
collection DOAJ
description The scientific literature provides extensive evidence of widespread magnesium deficiency and the potential need for magnesium repletion in diverse medical conditions. Magnesium is an essential element required as a cofactor for over 300 enzymatic reactions and is thus necessary for the biochemical functioning of numerous metabolic pathways. Inadequate magnesium status may impair biochemical processes dependent on sufficiency of this element. Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for magnesium, a deficiency problem contributing to various health conditions. This review assesses available medical and scientific literature on health issues related to magnesium. A traditional integrated review format was utilized for this study. Level I evidence supports the use of magnesium in the prevention and treatment of many common health conditions including migraine headache, metabolic syndrome, diabetes, hyperlipidemia, asthma, premenstrual syndrome, preeclampsia, and various cardiac arrhythmias. Magnesium may also be considered for prevention of renal calculi and cataract formation, as an adjunct or treatment for depression, and as a therapeutic intervention for many other health-related disorders. In clinical practice, optimizing magnesium status through diet and supplementation appears to be a safe, useful, and well-documented therapy for several medical conditions.
format Article
id doaj-art-ed3f38021c734c3f9a2e6e8786358d26
institution Kabale University
issn 2090-908X
language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Scientifica
spelling doaj-art-ed3f38021c734c3f9a2e6e8786358d262025-02-03T05:48:06ZengWileyScientifica2090-908X2017-01-01201710.1155/2017/41793264179326The Importance of Magnesium in Clinical HealthcareGerry K. Schwalfenberg0Stephen J. Genuis1Department of Family Medicine, University of Alberta, No. 301, 9509-156 Street, Edmonton, AB, T5P 4J5, CanadaFaculty of Medicine, University of Alberta, 2935-66 Street, Edmonton, AB, T6K 4C1, CanadaThe scientific literature provides extensive evidence of widespread magnesium deficiency and the potential need for magnesium repletion in diverse medical conditions. Magnesium is an essential element required as a cofactor for over 300 enzymatic reactions and is thus necessary for the biochemical functioning of numerous metabolic pathways. Inadequate magnesium status may impair biochemical processes dependent on sufficiency of this element. Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for magnesium, a deficiency problem contributing to various health conditions. This review assesses available medical and scientific literature on health issues related to magnesium. A traditional integrated review format was utilized for this study. Level I evidence supports the use of magnesium in the prevention and treatment of many common health conditions including migraine headache, metabolic syndrome, diabetes, hyperlipidemia, asthma, premenstrual syndrome, preeclampsia, and various cardiac arrhythmias. Magnesium may also be considered for prevention of renal calculi and cataract formation, as an adjunct or treatment for depression, and as a therapeutic intervention for many other health-related disorders. In clinical practice, optimizing magnesium status through diet and supplementation appears to be a safe, useful, and well-documented therapy for several medical conditions.http://dx.doi.org/10.1155/2017/4179326
spellingShingle Gerry K. Schwalfenberg
Stephen J. Genuis
The Importance of Magnesium in Clinical Healthcare
Scientifica
title The Importance of Magnesium in Clinical Healthcare
title_full The Importance of Magnesium in Clinical Healthcare
title_fullStr The Importance of Magnesium in Clinical Healthcare
title_full_unstemmed The Importance of Magnesium in Clinical Healthcare
title_short The Importance of Magnesium in Clinical Healthcare
title_sort importance of magnesium in clinical healthcare
url http://dx.doi.org/10.1155/2017/4179326
work_keys_str_mv AT gerrykschwalfenberg theimportanceofmagnesiuminclinicalhealthcare
AT stephenjgenuis theimportanceofmagnesiuminclinicalhealthcare
AT gerrykschwalfenberg importanceofmagnesiuminclinicalhealthcare
AT stephenjgenuis importanceofmagnesiuminclinicalhealthcare