Integrated bioinformatics and experimental validation identify lysosome and immune infiltration-related genes as therapeutic targets in late-onset major depressive disorder
Abstract This study leverages bioinformatics to identify differential genes linked to lysosomal alterations in late-onset major depressivedisorder (LOD) patients and explores potential therapeutic drugs. We analyzed differential genes in the GSE76826 dataset usingWGCNA to identify modules associated...
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| Main Authors: | Jian-Zhen Hu, Yao Gao, Xiao-Na Song, Dan Wang, Xin-Zhe Du, Xiao Wang, Xiao-Dong Hu, Sha Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-10283-9 |
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