Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application
This study aims to provide a comprehensive review of the ethical, legal and social issues in human brain organoid research, with a view to different types of research and applications: in vitro research, transplantation into non-human animals, and biocomputing. Despite the academic and societal atte...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-03-01
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| Series: | European Journal of Cell Biology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0171933524000876 |
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| author | Masanori Kataoka Takuya Niikawa Naoya Nagaishi Tsung-Ling Lee Alexandre Erler Julian Savulescu Tsutomu Sawai |
| author_facet | Masanori Kataoka Takuya Niikawa Naoya Nagaishi Tsung-Ling Lee Alexandre Erler Julian Savulescu Tsutomu Sawai |
| author_sort | Masanori Kataoka |
| collection | DOAJ |
| description | This study aims to provide a comprehensive review of the ethical, legal and social issues in human brain organoid research, with a view to different types of research and applications: in vitro research, transplantation into non-human animals, and biocomputing. Despite the academic and societal attention on the possibility that human brain organoids may be conscious, we have identified diverse issues in human brain organoid research and applications. To guide the complex terrain of human brain organoid research and applications, a multidisciplinary approach that integrates ethical, legal, and social perspectives is essential. |
| format | Article |
| id | doaj-art-ed348e1c7f6b4b2f9f4cc70dbe708162 |
| institution | Kabale University |
| issn | 0171-9335 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | European Journal of Cell Biology |
| spelling | doaj-art-ed348e1c7f6b4b2f9f4cc70dbe7081622025-01-23T05:26:14ZengElsevierEuropean Journal of Cell Biology0171-93352025-03-011041151470Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and applicationMasanori Kataoka0Takuya Niikawa1Naoya Nagaishi2Tsung-Ling Lee3Alexandre Erler4Julian Savulescu5Tsutomu Sawai6Uehiro Division for Applied Ethics, Graduate School of Humanities and Social Sciences, Hiroshima University, Hiroshima, JapanGraduate School of Humanities, Kobe University, Hyogo, JapanGraduate School of Interdisciplinary Information Studies, The University of Tokyo, Tokyo, JapanGraduate Institute of Health and Biotechnology Law, Taipei Medical University, Taipei, TaiwanInstitute of Philosophy of Mind and Cognition, National Yang Ming Chiao Tung University, TaiwanCentre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Oxford Uehiro Centre for Practical Ethics, Faculty of Philosophy, University of Oxford, Oxford, UK; Biomedical Ethics Research Group, Murdoch Children’s Research Institute, Australia; Melbourne Law School, The University of Melbourne, AustraliaUehiro Division for Applied Ethics, Graduate School of Humanities and Social Sciences, Hiroshima University, Hiroshima, Japan; Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Graduate School of Humanities and Social Sciences, Hiroshima University, Hiroshima, Japan; Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Kyoto, Japan; Corresponding author at: 1-7-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 732-8521, Japan.This study aims to provide a comprehensive review of the ethical, legal and social issues in human brain organoid research, with a view to different types of research and applications: in vitro research, transplantation into non-human animals, and biocomputing. Despite the academic and societal attention on the possibility that human brain organoids may be conscious, we have identified diverse issues in human brain organoid research and applications. To guide the complex terrain of human brain organoid research and applications, a multidisciplinary approach that integrates ethical, legal, and social perspectives is essential.http://www.sciencedirect.com/science/article/pii/S0171933524000876ELSIBrain organoidChimeraBiocomputingEthicsPublic engagement |
| spellingShingle | Masanori Kataoka Takuya Niikawa Naoya Nagaishi Tsung-Ling Lee Alexandre Erler Julian Savulescu Tsutomu Sawai Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application European Journal of Cell Biology ELSI Brain organoid Chimera Biocomputing Ethics Public engagement |
| title | Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application |
| title_full | Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application |
| title_fullStr | Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application |
| title_full_unstemmed | Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application |
| title_short | Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application |
| title_sort | beyond consciousness ethical legal and social issues in human brain organoid research and application |
| topic | ELSI Brain organoid Chimera Biocomputing Ethics Public engagement |
| url | http://www.sciencedirect.com/science/article/pii/S0171933524000876 |
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