Ethyl Acetate Extract of <i>Cichorium glandulosum</i> Activates the P21/Nrf2/HO-1 Pathway to Alleviate Oxidative Stress in a Mouse Model of Alcoholic Liver Disease

Ethyl Acetate Extract of <i>Cichorium glandulosum</i> Activates the P21/Nrf2/HO-1 Pathway to Alleviate Oxidative Stress in a Mouse Model of Alcoholic Liver Disease

Background: Alcoholic liver disease (ALD) is a significant global health concern, primarily resulting from chronic alcohol consumption, with oxidative stress as a key driver. The ethyl acetate extract of <i>Cichorium glandulosum</i> (CGE) exhibits antioxidant and hepatoprotective propert...

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Bibliographic Details
Main Authors: Shuwen Qi, Chunzi Zhang, Junlin Yan, Xiaoyan Ma, Yewei Zhong, Wenhui Hou, Juan Zhang, Tuxia Pang, Xiaoli Ma
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Metabolites
Subjects:
<i>Cichorium glandulosum</i>
alcoholic liver disease
oxidative stress
transcriptomics
network pharmacology
Online Access:https://www.mdpi.com/2218-1989/15/1/41
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https://www.mdpi.com/2218-1989/15/1/41

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