Targeting Caveolin‐1 in Multiple Myeloma Cells Enhances Chemotherapy and Natural Killer Cell‐Mediated Immunotherapy

Targeting Caveolin‐1 in Multiple Myeloma Cells Enhances Chemotherapy and Natural Killer Cell‐Mediated Immunotherapy

Abstract The cell membrane transport capacity and surface targets of multiple myeloma (MM) cells heavily influence chemotherapy and immunotherapy. Here, it is found that caveolin‐1 (CAV1), a primary component of membrane lipid rafts and caveolae, is highly expressed in MM cells and is associated wit...

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Bibliographic Details
Main Authors: Dewen Zhan, Zhimin Du, Shang Zhang, Juanru Huang, Jian Zhang, Hui Zhang, Zhongrui Liu, Eline Menu, Jinheng Wang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
caveolin‐1
glutathione metabolism
immunotherapy
multiple myeloma
natural killer cell
redox homeostasis
Online Access:https://doi.org/10.1002/advs.202408373
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