Self-priming of Plk1 binding to BubR1 ensures accurate mitotic progression

Self-priming of Plk1 binding to BubR1 ensures accurate mitotic progression

Abstract Plk1 is a key mitotic kinase that localizes to distinct subcellular structures to promote accurate mitotic progression. Plk1 recruitment depends on direct interaction between polo-box domain (PBD) on Plk1 and PBD binding motif (PBD BM) on the interactors. However, recent study showed that P...

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Main Authors: Chunlin Song, Mingzhe Zhang, Thomas Kruse, Mads Harder Møller, Blanca López-Méndez, Yuqing Zhang, Yujing Zhai, Ying Wang, Tingting Lei, Arminja N. Kettenbach, Jakob Nilsson, Gang Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07205-2
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https://doi.org/10.1038/s42003-024-07205-2

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