The known unknowns of the Hsp90 chaperone
Molecular chaperones are vital proteins that maintain protein homeostasis by assisting in protein folding, activation, degradation, and stress protection. Among them, heat-shock protein 90 (Hsp90) stands out as an essential proteostasis hub in eukaryotes, chaperoning hundreds of ‘clients’ (substrate...
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Main Authors: | Laura-Marie Silbermann, Benjamin Vermeer, Sonja Schmid, Katarzyna Tych |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2024-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/102666 |
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