Confirmatory identification and antibiotics resistance profiling of Pseudomonas aeruginosa: a laboratory-based study
Pseudomonas aeruginosa is a significant opportunistic pathogen frequently found in hospital environments and sewage systems, posing a challenge due to its intrinsic resistance to multiple antibiotics. Five isolates of Pseudomonas aeruginosa were collected from the Ahmadu Bello University Teaching H...
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| Format: | Article |
| Language: | English |
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Universidade Estadual de Maringá
2025-01-01
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| Series: | Acta Scientiarum: Biological Sciences |
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| Online Access: | https://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/73071 |
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| author | Hafsa Abdulhamid Abdulsalam |
| author_facet | Hafsa Abdulhamid Abdulsalam |
| author_sort | Hafsa Abdulhamid Abdulsalam |
| collection | DOAJ |
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Pseudomonas aeruginosa is a significant opportunistic pathogen frequently found in hospital environments and sewage systems, posing a challenge due to its intrinsic resistance to multiple antibiotics. Five isolates of Pseudomonas aeruginosa were collected from the Ahmadu Bello University Teaching Hospital, Shika Zaria and subjected to Gram staining and biochemical tests for initial identification. Four isolates were confirmed to be Pseudomonas aeruginosa based on these tests. Antibiotic susceptibility testing was performed to assess their resistance profiles, focusing on Imipenem and Ofloxacin. All four confirmed Pseudomonas aeruginosa isolates demonstrated resistance to Imipenem, a carbapenem antibiotic commonly used in clinical settings. Conversely, these isolates showed sensitivity to Ofloxacin, an alternative antibiotic with implications for treatment strategies against Pseudomonas aeruginosa infections. The observed resistance to Imipenem underscores ongoing challenges in treating Pseudomonas aeruginosa infections, emphasizing the need for alternative therapeutic options such as phage therapy.
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| format | Article |
| id | doaj-art-ec6baaea4a9140968e359ae376c4718b |
| institution | Kabale University |
| issn | 1679-9283 1807-863X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Universidade Estadual de Maringá |
| record_format | Article |
| series | Acta Scientiarum: Biological Sciences |
| spelling | doaj-art-ec6baaea4a9140968e359ae376c4718b2025-01-22T20:10:24ZengUniversidade Estadual de MaringáActa Scientiarum: Biological Sciences1679-92831807-863X2025-01-0146110.4025/actascibiolsci.v46i1.73071Confirmatory identification and antibiotics resistance profiling of Pseudomonas aeruginosa: a laboratory-based studyHafsa Abdulhamid Abdulsalam0Ahmadu Bello University Pseudomonas aeruginosa is a significant opportunistic pathogen frequently found in hospital environments and sewage systems, posing a challenge due to its intrinsic resistance to multiple antibiotics. Five isolates of Pseudomonas aeruginosa were collected from the Ahmadu Bello University Teaching Hospital, Shika Zaria and subjected to Gram staining and biochemical tests for initial identification. Four isolates were confirmed to be Pseudomonas aeruginosa based on these tests. Antibiotic susceptibility testing was performed to assess their resistance profiles, focusing on Imipenem and Ofloxacin. All four confirmed Pseudomonas aeruginosa isolates demonstrated resistance to Imipenem, a carbapenem antibiotic commonly used in clinical settings. Conversely, these isolates showed sensitivity to Ofloxacin, an alternative antibiotic with implications for treatment strategies against Pseudomonas aeruginosa infections. The observed resistance to Imipenem underscores ongoing challenges in treating Pseudomonas aeruginosa infections, emphasizing the need for alternative therapeutic options such as phage therapy. https://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/73071Pseudomonas aeruginosa; antibiotics; resistance; profiling |
| spellingShingle | Hafsa Abdulhamid Abdulsalam Confirmatory identification and antibiotics resistance profiling of Pseudomonas aeruginosa: a laboratory-based study Acta Scientiarum: Biological Sciences Pseudomonas aeruginosa; antibiotics; resistance; profiling |
| title | Confirmatory identification and antibiotics resistance profiling of Pseudomonas aeruginosa: a laboratory-based study |
| title_full | Confirmatory identification and antibiotics resistance profiling of Pseudomonas aeruginosa: a laboratory-based study |
| title_fullStr | Confirmatory identification and antibiotics resistance profiling of Pseudomonas aeruginosa: a laboratory-based study |
| title_full_unstemmed | Confirmatory identification and antibiotics resistance profiling of Pseudomonas aeruginosa: a laboratory-based study |
| title_short | Confirmatory identification and antibiotics resistance profiling of Pseudomonas aeruginosa: a laboratory-based study |
| title_sort | confirmatory identification and antibiotics resistance profiling of pseudomonas aeruginosa a laboratory based study |
| topic | Pseudomonas aeruginosa; antibiotics; resistance; profiling |
| url | https://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/73071 |
| work_keys_str_mv | AT hafsaabdulhamidabdulsalam confirmatoryidentificationandantibioticsresistanceprofilingofpseudomonasaeruginosaalaboratorybasedstudy |