Localised delivery of interleukin-13 from a PLGA microparticle embedded GelMA hydrogel improves functional and histopathological recovery in a mouse contusion spinal cord injury model

Localised delivery of interleukin-13 from a PLGA microparticle embedded GelMA hydrogel improves functional and histopathological recovery in a mouse contusion spinal cord injury model

Spinal cord injury (SCI) is a severe neurological condition with limited regenerative capacity and no effective curative treatments. Interleukin-13 (IL-13), an immunomodulatory cytokine, has shown therapeutic potential by promoting alternative immune activation and improving recovery after SCI in mi...

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Main Authors: Ciara M. Walsh, Ruth Colbert, James P. Reynolds, Emily Dunne, Emmanuelle D. Aiyegbusi, Ross O'Carroll, Jacek K. Wychowaniec, Takahiro Masuda, Klaus-Peter Knobeloch, Marco Prinz, Dermot F. Brougham, Dearbhaile Dooley
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-11-01
Series:Bioactive Materials
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25003111
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