Differential quantities of immune checkpoint-expressing CD8 T cells in soft tissue sarcoma subtypes

Introduction Local T-cell immunity is recognized for its contribution to the evolution and therapy response of various carcinomas. Here, we investigated characteristics of tumor-infiltrating lymphocytes (TILs), as well as T-cell evasive mechanisms in different soft tissue sarcoma (STS) subtypes.Meth...

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Bibliographic Details
Main Authors: Cornelis Verhoef, Reno Debets, Yarne Klaver, Stefan Sleijfer, Dirk Grünhagen, Rebecca Wijers, Maud Rijnders, Astrid Oostvogels, Marcel Smid, Cor Lamers
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000271.full
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