Simultaneous detection of human neutrophil elastase and cathepsin G on a single substrate using a fluorometric quantum dots probe and chemometric models

Simultaneous detection of human neutrophil elastase and cathepsin G on a single substrate using a fluorometric quantum dots probe and chemometric models

Human neutrophil elastase (HNE) and cathepsin G (CatG) are crucial proteolytic enzymes involved in the pathophysiology of chronic wounds. High levels of these enzymes indicate prolonged inflammation and impaired healing processes, making their discrimination and quantification essential for effectiv...

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Bibliographic Details
Main Authors: Fátima A.R. Mota, Rafael C. Castro, David S.M. Ribeiro, João L.M. Santos, Ricardo N.M.J. Páscoa, Marieta L.C. Passos, M. Lúcia M.F.S. Saraiva
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Biosensors and Bioelectronics: X
Subjects:
Chronic wounds
Enzymes
Quantum dots
Chemometrics
Machine learning
Data analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2590137024001353
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