Study protocol. TRAAPREVIA—TRAnexamic acid for preventing blood loss following a cesarean delivery in women with a placenta pREVIA or low-lying placenta: a multicenter randomized, double blind, placebo controlled trial

Abstract Background Placentas that are previa or low-lying are a major cause of severe postpartum hemorrhage (PPH). Tranexamic acid, by inhibiting the fibrinolytic pathway and protecting blood clots from degradation, is a promising drug for preventing blood loss after childbirth, especially in high-...

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Main Authors: Loïc Sentilhes, Hugo Madar, Amélie Ifrah, Jean-Marie Chrétien, Catherine Deneux-Tharaux, the TRAAPREVIA Study Group, the Groupe de Recherche en Obstétrique et Gynécologie (GROG)
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Pregnancy and Childbirth
Subjects:
Online Access:https://doi.org/10.1186/s12884-025-07682-1
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