Dietary secoisolariciresinol diglucoside ameliorates high-fat diet-induced atherosclerosis via regulating immunological inflammation and reshaping gut microbiota in ApoE-/- mice

Dietary secoisolariciresinol diglucoside ameliorates high-fat diet-induced atherosclerosis via regulating immunological inflammation and reshaping gut microbiota in ApoE-/- mice

Secoisolariciresinol diglucoside (SDG) has shown a variety of biological activities, but its impact on atherosclerosis (AS) remains poorly understood. This study investigated the potential of SDG in preventing and treating AS. Firstly, SDG administration ameliorated atherosclerotic lesion, lipid ind...

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Bibliographic Details
Main Authors: Yiwei Li, Jing Wang, Jian Liu, Ting Wang, Yuanyuan Liu, Yajuan Liu, Li Guo, Zhixia Bai, Wenke Shen, Ru Yan, Huiyan Ma, Juan Liu, Hao Wang, Xiaoxia Zhang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Functional Foods
Subjects:
Secoisolariciresinol diglucoside
Atherosclerosis
Anti-inflammation
Gut microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624006455
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