Elucidating the specific mechanisms of the gut-brain axis: the short-chain fatty acids-microglia pathway

Elucidating the specific mechanisms of the gut-brain axis: the short-chain fatty acids-microglia pathway

Abstract In recent years, the gut microbiota has been increasingly recognized for its influence on various central nervous system diseases mediated by microglia, yet the underlying mechanisms remain unclear. As key metabolites of the gut microbiota, short-chain fatty acids (SCFAs) have emerged as a...

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Bibliographic Details
Main Authors: Qingyu Cao, Mengmeng Shen, Ruoqiu Li, Yan Liu, Zhen Zeng, Jidong Zhou, Dejun Niu, Quancai Zhang, Rongrong Wang, Jingchun Yao, Guimin Zhang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Neuroinflammation
Subjects:
Gut microbiota
Short-Chain fatty acids
Microglia
Neurological diseases
Online Access:https://doi.org/10.1186/s12974-025-03454-y
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https://doi.org/10.1186/s12974-025-03454-y

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