Therapeutic Drug Monitoring-Based Population Pharmacokinetics of Amikacin in Patients at a Teaching Hospital

Therapeutic Drug Monitoring-Based Population Pharmacokinetics of Amikacin in Patients at a Teaching Hospital

<b>Background</b>: Amikacin is still an essential antimicrobial to treat life-threatening infections, including multidrug-resistant microorganisms. The effectiveness of treatment has been correlated with the Cmax/MIC ratio, with a ratio of 8 being recommended, which is difficult to reach...

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Main Authors: Nadine Arnold Steffens, Estevan Sonego Zimmermann, Francine Johansson Azeredo, Rafael Linden, Luis Junior Finatto, Roberta Zilles Hahn, Alexandre Vargas Schwarzbold, Liliane Souto Pacheco, Natália Brucker
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Antibiotics
Subjects:
aminoglycosides
popPK
drug monitoring
antibiotics
Monolix
Online Access:https://www.mdpi.com/2079-6382/14/6/531
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