Legionella pneumophila IrsA, a novel, iron-regulated exoprotein that facilitates growth in low-iron conditions and modulates biofilm formation

Legionella pneumophila IrsA, a novel, iron-regulated exoprotein that facilitates growth in low-iron conditions and modulates biofilm formation

ABSTRACT To discover new factors that are involved in iron acquisition by Legionella pneumophila, we used RNA-Seq to identify the genes that are most highly induced when virulent strain 130b is cultured in a low-iron chemically defined medium. Among other things, this revealed 14915, a heretofore un...

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Bibliographic Details
Main Authors: Alberto E. Lopez, Joshua Mayoral, Huaixin Zheng, Nicholas P. Cianciotto
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Series:Microbiology Spectrum
Subjects:
Legionella pneumophila
RNA-Seq
iron acquisition
FeoB
T2SS
type II secretion
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02313-24
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https://journals.asm.org/doi/10.1128/spectrum.02313-24

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