Study of pathogenesis and immune response at experimental infection of broiler chicks with avian metapneumovirus subtype В
Experimental infection of 7-day-old chicks with the isolate of avian metapneumovirus Subtype В induced mild signs of respiratory infection and swelled infraorbital sinuses in 5-15 days post infection. Lesions in tissues of trachea, nasal passages and primary lymphoid organs were reported. Using real...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Da Vinci Media
2018-04-01
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| Series: | Ветеринария сегодня |
| Subjects: | |
| Online Access: | https://veterinary.arriah.ru/jour/article/view/269 |
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| Summary: | Experimental infection of 7-day-old chicks with the isolate of avian metapneumovirus Subtype В induced mild signs of respiratory infection and swelled infraorbital sinuses in 5-15 days post infection. Lesions in tissues of trachea, nasal passages and primary lymphoid organs were reported. Using real-time RT-PCR avian metapneumovirus genome was detected in the upper part of the respiratory tract, infraorbital sinuses and Harderian gland within 2-12 days post infection. The immune response was characterized by formation of humoral and local antibodies in 7-21 days post infection. In 3 days post infection increased percentage of CD8a+ T-cell subpopulation was reported in blood and spleen of the infected chicks. |
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| ISSN: | 2304-196X 2658-6959 |