Contribution of Filopodia to Cell Migration: A Mechanical Link between Protrusion and Contraction

Numerous F-actin containing structures are involved in regulating protrusion of membrane at the leading edge of motile cells. We have investigated the structure and dynamics of filopodia as they relate to events at the leading edge and the function of the trailing actin networks. We have found tha...

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Bibliographic Details
Main Authors: Fei Xue, Deanna M. Janzen, David A. Knecht
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2010/507821
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