Emergence of power law distributions in protein-protein interaction networks through study bias

Emergence of power law distributions in protein-protein interaction networks through study bias

Degree distributions in protein-protein interaction (PPI) networks are believed to follow a power law (PL). However, technical and study biases affect the experimental procedures for detecting PPIs. For instance, cancer-associated proteins have received disproportional attention. Moreover, bait prot...

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Bibliographic Details
Main Authors: David B Blumenthal, Marta Lucchetta, Linda Kleist, Sándor P Fekete, Markus List, Martin H Schaefer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
protein-protein interaction networks
power law distributions
study bias
Online Access:https://elifesciences.org/articles/99951
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https://elifesciences.org/articles/99951

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