Altered heme metabolism and hemoglobin concentration due to empirical antibiotics-induced gut dysbiosis in preterm infants

Altered heme metabolism and hemoglobin concentration due to empirical antibiotics-induced gut dysbiosis in preterm infants

Background: High-risk infants are usually treated with empirical antibiotics after birth, regardless of the evidence of infection; however, their gut microbiome and metabolome have seldom been studied. This study investigated the influence of antibiotic exposure on the gut microbiome and associated...

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Main Authors: Seung Hyun Kim, Min‑Jin Kwak, Jae Kyoon Hwang, Jihyun Keum, Hee Yeon Jin, Chan-Yeong Lee, Rahul Sadashiv Tanpure, Yong Joo Kim, Jeong-Kyu Hoh, Jae Yong Park, Woojin Chung, Byong-Hun Jeon, Hyun-Kyung Park
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Antibiotics
Preterm infants
Gut microbiome
16S rRNA gene
Illumina sequencing
PICRUSt2
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025000765
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