Flow-Induced Shear Stress Combined with Microtopography Inhibits the Differentiation of Neuro-2a Cells

Flow-Induced Shear Stress Combined with Microtopography Inhibits the Differentiation of Neuro-2a Cells

Considering that neurological injuries cannot typically self-recover, there is a need to develop new methods to study neuronal outgrowth in a controllable manner in vitro. In this study, a precise flow-controlled microfluidic system featuring custom-designed chambers that integrate laser-microstruct...

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Bibliographic Details
Main Authors: Eleftheria Babaliari, Paraskevi Kavatzikidou, Dionysios Xydias, Sotiris Psilodimitrakopoulos, Anthi Ranella, Emmanuel Stratakis
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Micromachines
Subjects:
neuronal differentiation
microfluidics
microfluidic flow
shear stress
laser fabrication
topography
Online Access:https://www.mdpi.com/2072-666X/16/3/341
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