Cytochrome P450 monooxygenase-mediated eicosanoid pathway: A potential mechanistic linkage between dietary fatty acid consumption and colon cancer risk

Human consumption of linoleic acid (LA, 18:2ω-6, abundant in vegetable oils) is very high. Animal experiments showed that excessive LA intake increased azoxymethane-induced colon tumorigenesis, however, the impact of excessive LA on colon cancer in human is not conclusive, making it difficult to mak...

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Bibliographic Details
Main Authors: Weicang Wang, Jianan Zhang, Guodong Zhang
Format: Article
Language:English
Published: Tsinghua University Press 2019-12-01
Series:Food Science and Human Wellness
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453019301211
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